Attenuated psychotic symptoms, as defined in Criterion A, are psychosis-like but below the
threshold for a full psychotic disorder. Compared with psychotic disorders, the symptoms
are less severe and more transient, and insight is relatively maintained. A diagnosis of attenuated
psychosis syndrome requires state psychopathology associated with functional
impairment rather than long-standing trait pathology. The psychopathology has not progressed
to full psychotic severity. Attenuated psychosis syndrome is a disorder based on the
manifest pathology and impaired function and distress. Changes in experiences and behaviors are noted by the individual and/or others, suggesting a change in mental state (i.e., the
symptoms are of sufficient severity or frequency to warrant clinical attention) (Criterion A).
Attenuated delusions (Criterion A1) may have suspiciousness/persecutory ideational content,
including persecutory ideas of reference. The individual may have a guarded, distrustful
attitude. When the delusions are moderate in severity, the individual views others as
untrustworthy and may be hypervigilant or sense ill will in others. When the delusions are
severe but still within the attenuated range, the individual entertains loosely organized beliefs
about danger or hostile intention, but the delusions do not have the fixed nature that is
necessary for the diagnosis of a psychotic disorder. Guarded behavior in the interview can
interfere with the ability to gather information. Reality testing and perspective can be elicited
with nonconfirming evidence, but the propensity for viewing the world as hostile and
dangerous remains strong. Attenuated delusions may have grandiose content presenting as
an unrealistic sense of superior capacity. When the delusions are moderate, the individual
harbors notions of being gifted, influential, or special. When the delusions are severe, the individual
has beliefs of superiority that often alienate friends and worry relatives. Thoughts
of being special may lead to unrealistic plans and investments, yet skepticism about these attitudes
can be elicited with persistent questioning and confrontation.
Attenuated hallucinations (Criterion A2) include alterations in sensory perceptions,
usually auditory and/or visual. When the hallucinations are moderate, the sounds and
images are often unformed (e.g., shadows, trails, halos, murmurs, rumbling), and they are
experienced as unusual or puzzling. When the hallucinations are severe, these experiences
become more vivid and frequent (i.e., recurring illusions or hallucinations that capture attention
and affect thinking and concentration). These perceptual abnormalities may disrupt
behavior, but skepticism about their reality can still be induced.
Disorganized communication (Criterion A3) may manifest as odd speech (vague, metaphorical,
overelaborate, stereotyped), unfocused speech (confused, muddled, too fast or too
slow, wrong words, irrelevant context, off track), or meandering speech (circumstantial, tangential).
When the disorganization is moderately severe, the individual frequently gets into
irrelevant topics but responds easily to clarifying questions. Speech may be odd but understandable.
At the moderately severe level, speech becomes meandering and circumstantial,
and when the disorganization is severe, the individual fails to get to the point without
external guidance (tangential). At the severe level, some thought blocking and/or loose associations
may occur infrequently, especially when the individual is under pressure, but reorienting
questions quickly return structure and organization to the conversation.
The individual realizes that changes in mental state and/or in relationships are taking
place. He or she maintains reasonable insight into the psychotic-like experiences and generally
appreciates that altered perceptions are not real and magical ideation is not compelling.
The individual must experience distress and/or impaired performance in social or role
functioning (Criterion D), and the individual or responsible others must note the changes
and express concern, such that clinical care is sought (Criterion A). Associated Features
The individual may experience magical thinking, perceptual aberrations, difficulty in concentration,
some disorganization in thought or behavior, excessive suspiciousness, anxiety,
social withdrawal, and disruption in sleep-wake cycle. Impaired cognitive function
and negative symptoms are often observed. Neuroimaging variables distinguish cohorts
with attenuated psychosis syndrome from normal control cohorts with patterns similar to,
but less severe than, that observed in schizophrenia. However, neuroimaging data is not
diagnostic at the individual level.